NBE DMPK Lead (all genders), limited for 2 years

Your Role:

At the intersection of scientific innovation and patient impact, this role places you at the heart of next-generation biotherapeutic development. As the NBE DMPK Lead, you will serve as the authoritative scientific expert for drug metabolism and pharmacokinetics across a portfolio of novel biological entities - including ADCs, AOCs, and multispecific biologics. You will define the DMPK strategy for each molecule, integrating PK, immunogenicity, and bioanalytical approaches to de-risk clinical development and drive health authority submissions. Applying Modeling and Simulation, you will generate data-driven insights to inform molecular design and translate preclinical findings into human dose predictions. Embedded in cross-functional project teams, you will guide peers and senior stakeholders - shaping the scientific direction of your projects.

This position is limited for two years.

Who You Are:

• You hold a degree or equivalent qualification in Pharmacokinetics, Pharmaceutical or Biotechnological Sciences, Biomedical or Chemical Engineering, Applied Mathematics, or a related biological or chemical discipline; a doctoral degree with relevant industry experience is typical for this level.
• You bring substantial professional experience in the pharmaceutical or biotechnology industry, with deep expertise in PK/PD concepts across drug discovery and development - including translational sciences and regulatory requirements for biotherapeutics such as ADCs, AOCs, and multispecific biologics.
• You have hands-on experience with quantitative modeling approaches, including M&S tools, population PK software, QSP platforms, or programming environments such as Python or R; experience with AI/ML applications in drug development is a strong advantage.
• You possess a solid understanding of adjacent disciplines - including pharmacology, toxicology, nonclinical safety, drug design, and bioanalytics - and can integrate insights across these areas to guide biotherapeutic engineering and optimization.
• You communicate complex scientific concepts clearly and confidently to diverse audiences, including cross-functional project teams and senior stakeholders, and are comfortable influencing decisions without direct authority.
• You are fluent in written and spoken English; proficiency in German or Italian is an advantage.
• You bring strong organizational skills, intercultural awareness, and the ability to manage multiple project commitments with a high degree of autonomy.

Department: HC-RD-X1U DMPK Project Support

Job Evaluation: AT / Expert 3