Master Thesis for Single Cell Analysis in Microfluidic Well Arrays for Cancer Immunotherapy (m/f/x)

Welcome to Hahn-Schickard: The research center for innovative microsystems technology. With a team of over 300 employees, we transform ideas into cross-industry solutions - from conception to production at three locations in Baden-Württemberg. At our Freiburg site, the emphasis is on developing analytical solutions in microsystems technology, particularly for point-of-care diagnostics.

For the area of Microfluidic Platforms in Freiburg, we offer from 01.10.2026

Master Thesis for Single Cell Analysis in Microfluidic Well Arrays for Cancer Immunotherapy (m/f/x)

Aim of the thesis

• Tumor infiltrating leucocytes (TIL) isolated from tumor tissue are promising for cancer therapy. TILs must be analyzed prior to therapeutic use.
• The goal of the thesis is to demonstrate how single TILs can be isolated in individual picoliter-microwells for later analysis on the single-cell level.

Your Tasks

• Concept Development: Literature research and systematic development of concepts for TIL single-cell-distribution in an existing microfluidic microtiter plate.
• Model Establishment: Find a suitable model for TIL cells for initial tests (e.g. microbeads or cell lines).
• Protocol Development: Test and optimize your own concepts in the lab including reference assays such as ELISA or digital PCR.

Your profile

• Studies: Biochemistry, Biotechnology, Molecular Biology, Medical Engineering, or a related STEM discipline with strong interest for life sciences.
• Skills: Lab experience (pipetting, microscopy, cell handling) required, experience with microfluidic systems or image analysis is a plus.
• Work Style: Independent and structured.
• Language: Good English or German

Our offer to you

• Innovative working environment: State-of-Art research institute with close links to industry
• Future-proof career: a wide range of possible assignments during and after your studies
• Training & Development: Benefit from attractive further training opportunities
• Health and lifestyle: Participation in first-class health programs such as Hansefit and other benefit programs
• Subsidy for meals
• Mobility support: partial refund of travel expenses while using public transport ÖPNV

Your Application

Mr. Christoph Stärk by phone +49 761 203-7404 or e-mail [email protected] will be pleased to answer any questions you may have.

If we you are interested, please send us your complete application documents (motivation letter/resume+CV/certificates/transcript of records), preferentially in one single PDF-document, quoting the internal reference number 26/3240/34

Ihre Ansprechpartnerin

Frau Antigoni Zouridaki

Kontakt

Hahn-Schickard gGmbH
Georges-Köhler-Allee 304
79110 Freiburg im Breisgau

[email protected]
0761 203 73200